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Home Antibody All anti-Bin1 antibodies

Anti-Bin1 Antibody

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SKU Description Amount Price Availability*  
TA318950 Rabbit polyclonal anti-Bin1 antibody 100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to residues surrounding amino acids 578 of mouse BIN-1
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.2 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4 ug/ml
Buffer100 µg (0.2mg/ml) immunoaffinity purified rabbit anti-Bin-1 polyclonal antibody in phosphate-buffered saline (PBS) containing 0.1% BSA, 30% glycerol, and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens bridging integrator 1 (BIN1), transcript variant 8
Alternative NameAMPH2; AMPHL; SH3P9
Database LinkNP_004296
Entrez Gene 274 Human
Entrez Gene 30948 Mouse
Entrez Gene 117028 Rat
FunctionBIN-1 is a tumor suppressor protein that was identified in a genetic screen for proteins that interact with the MCY oncoprotein. BIN-1 inhibits the oncogenic activity of MYC, possibly through activating or facilitating apoptosis. BIN is a short-lived protein with a half-life of about 2 hours.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of BIN-1 expression in Jurkat cells treated with (Lane 2) or without (Lane 1) camptothecin.
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