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Home Antibody All anti-SMAD7 antibodies

Anti-SMAD7 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318948
  • Rabbit polyclonal anti-Smad7 antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416991) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for SMAD7 (NM_005904)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide from human Smad 7
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4 ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit anti-Smad7 polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens SMAD family member 7 (SMAD7), transcript variant 1
Alternative NameCRCS3; MADH7; MADH8
Database LinkNP_005895
FunctionSmad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFß/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-ß and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFß signaling by interfering with TGFß-mediated phosphorylation of other Smad family members.
Related Pathway
TGF Beta Signaling Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Smad7 expression in Jurkat cell lysate (Lane 1& 2) and 3T3 cell lysate (Lane 3).

 

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