Home Antibody All anti-Fkbp1a antibodies
Also for Fkbp1a (NM_000801)
|Synthetic peptide surrounding amino acid 10 of mouse FKBP12|
|Human, mouse, rat
||WB: 0.5-4 ug/ml, IHC: 2-10ug/ml, IP: 2-10ug/ml
|100 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Homo sapiens FK506 binding protein 1A, 12kDa (FKBP1A), transcript variant 1|
|FKBP-12; FKBP-1A; FKBP1; FKBP12; PKC12; PKCI2; PPIASE|
Entrez Gene 2280 Human
Entrez Gene 14225 Mouse
Entrez Gene 25639 Rat
|FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway.|
TGF Beta Signaling Pathway
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Western blot analysis of FKBP12 expression in rat kidney tissue lysate.