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Home Antibody All anti-Hdac7 antibodies

Anti-Hdac7 Antibody

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SKU Description Amount Price Availability*  
TA318926 Rabbit polyclonal anti-HDAC7 antibody 100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 921 of murine HDAC7
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.2 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4 ug/ml, IHC: 20-40ug/ml, IP: 20-40ug/ml
Buffer100 µg (0.2 mg/ml) affinity purified rabbit anti-HDAC7 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens histone deacetylase 7 (HDAC7), transcript variant 4
Alternative NameHD7A; HDAC7A
Database LinkNP_001091886
Entrez Gene 51564 Human
Entrez Gene 56233 Mouse
Entrez Gene 84582 Rat
FunctionHuman HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of HDAC7 expression in mouse small intestine tissue lysate.
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