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Anti-DMD Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318925
  • Rabbit polyclonal anti-Dystrophin antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418279) , 20ug
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 3656 of human Dystrophin
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4ug/ml
Buffer100 µg (0.5 mg/ml) antigen affinity purified rabbit anti-Dystrophin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% Thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens dystrophin (DMD), transcript variant Dp40
Alternative NameBMD; CMD3B; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; MRX85
Database LinkNP_004010
FunctionDystrophin is one of the actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin expression is found in muscle brain tissues, where it is located to the inner surface of the plasma membrane. It is suggested that alternative splicing of the caboxy terminus allows dystrophin to interact with a variety of proteins. Loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and lack of dystrophin results in the loss of linkage between the cytoskeleton and extracellular matrix.
Related Pathway

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WB Image
Western blot analysis of Dystrophin expression in 3T3 cell lysate (Lane 1) and rat kidney tissue lysate (Lane 2).

 

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