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Home Antibody All anti-Wnt6 antibodies

Anti-Wnt6 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA318924 Rabbit polyclonal anti-Wnt-6 antibody 100ug $325 In Stock
LC401954 WNT6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 276 of mouse Wnt-6
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4 ug/ml, IHC: 10-20ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit Wnt-6 polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens wingless-type MMTV integration site family, member 6 (WNT6)
Alternative Namewingless-type MMTV integration site family, member 6
Database LinkNP_006513
Entrez Gene 7475 Human
Entrez Gene 22420 Mouse
Entrez Gene 316526 Rat
FunctionWnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. Wnt-1, which is essential for normal development of the embryonic nervous system, contributes to hyperplasia and tumorigenic progression when improperly expressed in mammary tissue. Wnt-3 is involved in tumorigenesis and Wnt-2 and Wnt-4 may be associated with abnormal proliferation in human breast tissue. Wnt-6 is involved in oncogenesis and is co-expressed with Wnt10 in colorectal cancer cell lines. The presence of cervical and breast cell carcinomas may indicate an over expression of Wnt-6.
Related PathwayStem cell relevant signaling - Wnt Signaling pathwaySecreted ProteinES Cell Differentiation/IPSTransmembraneAdult stem cellsCancer stem cells Wnt signaling pathwayHedgehog signaling pathwayMelanogenesisPathways in cancerBasal cell carcinoma

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of Wnt-6 expression in rat kidney tissue lysate.
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