Home Antibody All anti-Tlr3 antibodies
Also for Tlr3 (NM_003265)
|Synthetic peptide surrounding amino acid 805 of mouse TLR3|
|Human, mouse, rat
|PBS, pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal|
|Homo sapiens toll-like receptor 3 (TLR3)|
Entrez Gene 7098 Human
Entrez Gene 142980 Mouse
Entrez Gene 364594 Rat
|To date, at least ten members of the Toll family have been identified. TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial immune response. TLR3 recognizes double-stranded (ds) RNA, induces the activation of NF-kB, through MyD88-dependent and -independent pathways, and the production of type I interferons (IFNs). Similar to several other members of the TLR family, TLR3 has been reported to be expressed at a very low level on the surface of human fibroblast cell lines.|
|TransmembraneDruggable Genome Toll-like receptor signaling pathway|
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Western blot analysis of TLR3 expression in lysate from Jurkat cells (Lane 1 & 2) and 3T3 cells (Lane 3).