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Home Antibody All anti-Tlr4 antibodies

Anti-Tlr4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318891
  • Rabbit polyclonal anti-TLR4 antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC408575) , 20ug
100ug $325 3-7 Days
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OriGene Data

ImmunogenSynthetic peptide corresponding to residues surrounding amino acids 819 of rat TLR4
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit anti-TLR4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens toll-like receptor 4 (TLR4), transcript variant 3
Alternative NameARMD10; CD284; TLR-4; TOLL
Database LinkNP_003257
FunctionTLR4 (Toll-like receptor 4) is a mammalain homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB.
Related Pathway
Toll-like receptor signaling pathway

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WB Image
Western blot analysis of TLR4 in rat kidney tissue lysate.

 

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