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Home Antibody All anti-GNA15 antibodies

Anti-GNA15 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318890
  • Rabbit polyclonal anti-Ga15/16 antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419560) , 20ug Explanation
100ug 325 In Stock
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WB(1)
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Also for GNA15 (NM_002068)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 356of human G 15
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4ug/ml, IHC: 5-20ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit anti-Ga15 polyclonal antibody in PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens guanine nucleotide binding protein (G protein), alpha 15 (Gq class) (GNA15)
Alternative NameGNA16
Database LinkNP_002059
Entrez Gene 2769 Human
Entrez Gene 14676 Mouse
Entrez Gene 89788 Rat
FunctionGa16 is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of Ga16. The G protein is known to couple a large number of G protein-coupled receptors to PLC-ß and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of Ga15, a mouse orthologue of human Ga16, causes reduced C5a receptor signaling. Ga16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells.
Related PathwayDruggable Genome Calcium signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of G alpha-15 expression in 3T3 cell lysate.

 

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