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Home Antibody All anti-Mbd2 antibodies

Anti-Mbd2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318881
  • Rabbit polyclonal anti-MBD2a antibody
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 164 of rat MBD2a
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit anti- MBD2a polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens methyl-CpG binding domain protein 2 (MBD2), transcript variant 1
Alternative NameDMTase; NY-CO-41
Database LinkNP_003918
FunctionThe MBD family of proteins includes MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD2 is highly similar to MBD3 but only MBD2 targets the MeCP1 complex to methylate DNA. MBD2 has two isoforms, MBD2a and MBD2b. MBD2a is a 414 amino acids protein, whereas MBD2b lacks the 152 amino acids N-terminal extension. MBD2a interacts with RNA helicase A to enhance CREB-dependent gene exptression.
Related Pathway

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WB Image
Western blot analysis of MBD2a using Jurkat cell lysate.

 

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