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Anti-RB1 PHOSPHO Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA314432 Rabbit polyclonal Retinoblastoma (Ser608) antibody(Phospho-specific) 100ul $325 In Stock
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WB(2)
IHC(1)

OriGene Data

ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Retinoblastoma around the phosphorylation site of serine 608 (Y-L-SP-P-V).
Clone Name IsotypeIgG
Species ReactivityHuman (Identities = 100%, Positives = 100%); Mouse (Identities = 93%, Positives = 100%);Rat (Identities = 93%, Positives = 100%) Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:40000
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Note Retinoblastoma (Phospho-Ser608) antibody detects endogenous levels of Retinoblastoma only when phosphorylated at serine 608.

Reference Data

Target NameHomo sapiens RB transcriptional corepressor 1 (RB1)
Alternative NameOSRC; p105-Rb; pp110; PPP1R130; pRb; RB
Database LinkNP_000312
Entrez Gene 5925 Human
Entrez Gene 19645 Mouse
Entrez Gene 24708 Rat
Function
Related PathwayTranscription FactorsDruggable Genome Cell cyclePathways in cancerPancreatic cancerGliomaProstate cancerMelanomaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
Western blot analysis of extracts from Jurkat cells, treated with PMA (125ng/ml, 30mins), using Retinoblastoma (Phospho-Ser608) antibody.The lane on the right is treated with the synthesized peptide.
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WB Image
Western blot analysis of extracts from JK cells (Lane 2), using Retinoblastoma (Phospho-Ser608) Antibody. The lane on the left is treated with synthesized peptide.
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IHC Image
Immunohistochemistry analysis of paraffin-embedded human brain tissue using Retinoblastoma (Phospho-Ser608) antibody.The picture on the right is treated with the synthesized peptide.
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