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Anti-IRF3 PHOSPHO Antibody

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SKU Description Amount Price Availability*  
TA311897
  • Rabbit polyclonal IRF-3 (Ser386) antibody(Phospho-specific)
100ul $325 In Stock
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WB(2)

OriGene Data

ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human IRF-3 around the phosphorylation site of serine 386 (A-S-SP-L-E).
Clone Name IsotypeIgG
Species ReactivityHuman (Identities = 100%, Positives = 100%) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:500~1:3000, ELISA: 1:1000
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Note IRF-3 (Phospho-Ser386) antibody detects endogenous levels of IRF-3 only when phosphorylated at serine 386.

Reference Data

Target NameHomo sapiens interferon regulatory factor 3 (IRF3), transcript variant 1
Alternative NameMGC94729; interferon regulatory factor 3
Database LinkNP_001562
Entrez Gene 3661 Human
Function
Related PathwayTranscription FactorsDruggable Genome Toll-like receptor signaling pathwayRIG-I-like receptor signaling pathwayCytosolic DNA-sensing pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of extracts from HepG2cells, treated with EGF (200ng/ml, 30mins), using IRF-3 (Phospho-Ser386) antibody.The lane on the right is treated with the synthesized peptide.
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Western blot analysis of extracts from 293 cells (Lane 2) and colo cells (Lane 3), using IRF-3 (Phospho-Ser386) Antibody. The lane on the left is treated with synthesized peptide.
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