Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas Blood, Mar 2013; 121: 2563 - 2566.
[anti-HA]
Regulation of the PI3-K/Akt Survival Pathway in the Rat Endometrium Biol Reprod, Mar 2013; 88: 79.
[Akt3]
RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt159.
[LA]
Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements Haematologica, Mar 2013; 98: 404 - 408.
[JAK2]
ZPR1 is a zinc finger protein that acts as a signaling factor relaying proliferative growth signals from the cell surface to the nucleus. It binds to eukaryotic translation elongation factor 1alpha (eEF1 alpha) in response to growth stimuli, and is also involved in transcription and cell cycle regulation. ZPR1 interacts with survival motor neurons (SMN) proteins, co-localizing in small subnuclear structures (1). Moreover, ZPR1 is part of the cytoplasmic preimport snRNP complex formed by SMN, Sm proteins, snurportin 1, and importin beta (2).
Related Pathway
EGFR1 Signaling Pathway
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Western blot analysis on (A) human stomach, (B) fetal liver, (C) colon cancer, (D) BxPC-3, (E) HepG2, (F) Caco-2, (G) MCF-7, and (H) Jurkat lysates using anti-ZPR1 RabMAb.