OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431.
[anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780.
[SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052
[anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210.
[NPR3] View All Citations >>
Home All anti-UBE2M antibodies
Anti-UBE2M Antibody EPR5333
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
Also for UBE2M (NM_003969)
Homo sapiens ubiquitin-conjugating enzyme E2M (UBE2M) hUbc12; UBC-RS2; UBC12 A synthetic peptide corresponding to residues on the C-terminus in human UBC12 was used as an immunogen. Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
EPR5333
Human, Mouse, Rat
(Protein A or G Sepharose )
WB, IHC
WB: 1:10,000 - 50,000; ICC: 1:50 - 100; IP: 1:10 - 100;
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBC12 is a member of the E2 ubiquitin-conjugating enzyme family. It is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin (1).
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WB Image
Western blot analysis on (A) 293T and (B) Ramos cell lysates using anti-UBC12 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human colonic adenocarcinoma tissue using anti-UBC12 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using anti-UBC12 RabMAb.
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