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Home Antibody All anti-TNFRSF11B antibodies

Anti-TNFRSF11B Antibody EPR3592

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311094
  • Rabbit Monoclonal antibody against Osteoprotegerin (TNFRSF11B)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419252) , 20ug
100ul 325 3-7 Days
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WB(2)
IHC(2)
IF(1)
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Also for TNFRSF11B (NM_002546)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Osteoprotegerin was used as an immunogen.
Clone NameEPR3592 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsIHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250; ICC: Use at an assay dependent concentration
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,IP or WB.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,IP or WB.

Reference Data

Target NameHomo sapiens tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B)
Alternative NameOCIF; OPG; TR1
Database LinkNP_002537
FunctionOsteoprotegerin is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. Osteoprotegerin specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification (1).
Related Pathway
Cytokine-cytokine receptor interaction

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-TNFRSF11B antibody [EPR3592]; Anti-Osteoprotegerin antibody [EPR3592] at 1/1000 dilution + fetal kidney lysate at 10 µg.Secondary.Goat-anti-rabbit HRP at 1/2000 dilution.Predicted band size : 46 kDa.Observed band size : 55 kDa .
WB Image
Western blot - Anti-TNFRSF11B antibody [EPR3592]; Anti-Osteoprotegerin antibody [EPR3592] at 1/1000 dilution + TNFRSF11B recombinant protein fragment at 10 µg.Secondary.Goat-anti-rabbit HRP at 1/2000 dilution.Predicted band size : 46 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TNFRSF11B antibody [EPR3592]; TA311094 at 1/100 dilution, staining TNFRSF11B in Formalin fixed Paraffin-embedded Human kidney tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TNFRSF11B antibody [EPR3592]; TA311094 at 1/100 dilution, staining TNFRSF11B in Formalin fixed Paraffin-embedded Human heart tissue by Immunohistochemistry.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-TNFRSF11B antibody [EPR3592]; TA311094, at 1/100 dilution, staining TNFRSF11B in HeLa cells.

 

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