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Anti-TEAD1 Antibody EPR5279
Also for TEAD1 (NM_021961)
|A synthetic peptide corresponding to residues on the C-terminus in human TCF13 / TEF1 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:10000 - 1:50000; FC: 1:100 - 1:500
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens TEA domain family member 1 (SV40 transcriptional enhancer factor) (TEAD1)|
|AA; NTEF-1; REF1; TCF-13; TCF13; TEAD-1; TEF-1|
|TCF13/TEF1 is a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor (1). It plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. TCF13/TEF1 binds specifically and cooperatively to the SPH and GT-IIC enhansons (2). It also binds M-CAT elements and regulates the development of cardiac, skeletal, and smooth muscles (3). Mutations in TCF13/TEF1 cause Sveinsson's chorioretinal atrophy (1).|
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Western blot - TEF1 antibody [EPR5279]; All lanes : Anti-TEF1 antibody [EPR5279] at 1/10000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : A673 cell lysate.Lane 3 : A431 cell lysate.Lane 4 : BxPC-3 cell lysate.Lane 5 : JAR cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 48 kDa.
Flow Cytometry - TEF1 antibody [EPR5279]; Flow cytometric analysis of permeabilized HeLa cells using TA311087 at a dilution of 1/100.