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Home All anti-SPINT2 antibodies
Anti-SPINT2 Antibody EPR6283(2)
Also for SPINT2 (NM_001166103)
Homo sapiens serine peptidase inhibitor, Kunitz type, 2 (SPINT2), transcript variant b
DIAR3; HAI-2; HAI2; Kop; PB
A synthetic peptide corresponding to residues in the extracellular domain of human HAI-2 was used as an immunogen.
Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Human, Mouse, Rat
WB: 1:1,000 - 10,000; IHC 1:100 - 250; ICC: 1:100 - 250; FC: 1:10 - 100;
HAI-2 is a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. It inhibits the HGF activator that prevents the formation of active hepatocyte growth factor. HAI-2 is a putative tumor suppressor, and mutations in this protein result in congenital sodium diarrhea (1).
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Western blot analysis on (A) fetal kidney, (B) MCF-7, (C) human small intestine, (D) Caco-2, and (E) PC-3 lysates using anti-HAI-2 RabMAb.
Immunofluorescent staining of MCF-7 cells using anti-HAI-2 RabMAb.