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Anti-SMARCE1 Antibody EPR8848
Also for SMARCE1 (NM_003079)
|A synthetic peptide corresponding to residues in human BAF57 was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC
||ICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt.
|Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 (SMARCE1)|
|BAF57 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for activation of proteins normally repressed by chromatin. It, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. BAF57 contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, BAF57 has no yeast counterpart (1). |
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Western blot - Anti-BAF57/SMARCE1 antibody [EPR8848]; All lanes : Anti-BAF57/SMARCE1 antibody [EPR8848] at 1/1000 dilution.Lane 1 : MCF-7 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : Raji cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 47 kDa.
Other-Anti-BAF57/SMARCE1 antibody [EPR8848](TA311072); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAF57/SMARCE1 antibody [EPR8848]; Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling BAF57/SMARCE1 with TA311072 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAF57/SMARCE1 antibody [EPR8848]; Immunohistochemical analysis of paraffin-embedded Human skin tissue labelling BAF57/SMARCE1 with TA311072 at 1/100 dilution.