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Home Antibody All anti-SMARCE1 antibodies

Anti-SMARCE1 Antibody EPR8848

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311072
  • Rabbit Monoclonal antibody against BAF57 (SMARCE1)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401073) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(2)
Assay(1)
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Also for SMARCE1 (NM_003079)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human BAF57 was used as an immunogen.
Clone NameEPR8848 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
Predicted MW Explanation 47 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 (SMARCE1)
Alternative NameBAF57
Database LinkNP_003070
Entrez Gene 6605 Human
Entrez Gene 57376 Mouse
Entrez Gene 303518 Rat
FunctionBAF57 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for activation of proteins normally repressed by chromatin. It, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. BAF57 contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, BAF57 has no yeast counterpart (1).
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-BAF57/SMARCE1 antibody [EPR8848]; All lanes : Anti-BAF57/SMARCE1 antibody [EPR8848] at 1/1000 dilution.Lane 1 : MCF-7 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : Raji cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 47 kDa.
Assay Image
Other-Anti-BAF57/SMARCE1 antibody [EPR8848](TA311072); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAF57/SMARCE1 antibody [EPR8848]; Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling BAF57/SMARCE1 with TA311072 at 1/100 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAF57/SMARCE1 antibody [EPR8848]; Immunohistochemical analysis of paraffin-embedded Human skin tissue labelling BAF57/SMARCE1 with TA311072 at 1/100 dilution.

 

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