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Home Antibody All anti-SMARCE1 antibodies

Anti-SMARCE1 Antibody EPR8848

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA311072
  • Rabbit Monoclonal antibody against BAF57 (SMARCE1)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401073) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(2)
Assay(1)
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Also for SMARCE1 (NM_003079)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human BAF57 was used as an immunogen.
Clone NameEPR8848 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
Predicted MW Explanation 47 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 (SMARCE1)
Alternative NameBAF57
Database LinkNP_003070
Entrez Gene 6605 Human
Entrez Gene 57376 Mouse
Entrez Gene 303518 Rat
FunctionBAF57 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for activation of proteins normally repressed by chromatin. It, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. BAF57 contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, BAF57 has no yeast counterpart (1).
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-BAF57/SMARCE1 antibody [EPR8848]; All lanes : Anti-BAF57/SMARCE1 antibody [EPR8848] at 1/1000 dilution.Lane 1 : MCF-7 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : Raji cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 47 kDa.
Assay Image
Other-Anti-BAF57/SMARCE1 antibody [EPR8848](TA311072); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAF57/SMARCE1 antibody [EPR8848]; Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling BAF57/SMARCE1 with TA311072 at 1/100 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAF57/SMARCE1 antibody [EPR8848]; Immunohistochemical analysis of paraffin-embedded Human skin tissue labelling BAF57/SMARCE1 with TA311072 at 1/100 dilution.

 

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