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Home Antibody All anti-SLC4A1 antibodies

Anti-SLC4A1 Antibody EPR1426

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311070
  • Rabbit Monoclonal antibody against AE1 (SLC4A1)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424786) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(2)
IF(1)
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Also for SLC4A1 (NM_000342)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human AE1 was used as an immunogen.
Clone NameEPR1426 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC/IF: Use at an assay dependent concentration
BufferDoes not react with Mouse, Rat. Is unsuitable for IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens solute carrier family 4 (anion exchanger), member 1 (Diego blood group) (SLC4A1)
Alternative NameAE1; BND3; CD233; DI; EMPB3; EPB3; FR; RTA1A; SW; WD; WD1; WR
Database LinkNP_000333
FunctionThe AE1 (anion exchanger, band 3) protein is expressed in erythrocytes and in the A-type intercalated cells of the kidney distal collecting tubule. In both cell types it mediates the electroneutral transport of chloride and bicarbonate ions across the lipid bilayer, and, in erythrocytes (1). AE1 is phosphorylated on Tyr8and Tyr21 by SYK. It has been suggested that, upon phosphorylation by p72syk, Tyr8, and Tyr21 act as docking sites for the SH2 domain of Lyn, which subsequently phosphorylates AE1 at additional secondary sites (2).
Related Pathway

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WB Image
Western blot - Band 3 antibody [EPR1426]; Anti-Band 3 antibody [EPR1426] at 1/1000 dilution + Red blood cell lysate at 10 µg.Predicted band size : 102 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Band 3 antibody [EPR1426]; TA311070, at 1/100 dilution, staining Band 3 in paraffin-embedded Human colon tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Band 3 antibody [EPR1426]; TA311070, at 1/100 dilution, staining Band 3 in paraffin-embedded Human lung tissue by Immunohistochemistry.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-Band 3 antibody [EPR1426]; TA311070 staining Band 3 in Rhesus monkey erythroid cells by Immunocytochemistry/ Immunofluorescence.Cells were fixed in methanol and then incubated with TA311070 at a 1/100 dilution for 1 hour. The secondary used was an FITC conjugated goat anti-rabbit polyclonal used at a 1/100 dilution.

 

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