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Home Antibody All anti-SESN1 antibodies

Anti-SESN1 Antibody EPR1930(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311066
  • Rabbit Monoclonal antibody against Sestrin-1 (SESN1)
100ul 325 In Stock
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WB(1)
FC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Sestrin-1 was used as an immunogen.
Clone NameEPR1930(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:100 - 1:500
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens sestrin 1 (SESN1), transcript variant 1
Alternative NamePA26; SEST1
Database LinkNP_055269
FunctionSestrin-1 is a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. Sestrin-1 mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. This protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of Sestrin-1 is a potential marker for exposure to radiation (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-SESN1 antibody [EPR1930(2)]; All lanes : Anti-SESN1 antibody [EPR1930(2)] at 1/1000 dilution.Lane 1 : Ramos cell lysate.Lane 2 : K562 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : C2C12 cell lysate.Lane 5 : NIH3T3 cell lysate.Lane 6 : F9 cell lysate.Lane 7 : JAR cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 57 kDa.</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>
Assay Image
Other-Anti-SESN1 antibody [EPR1930(2)](TA311066); Equilibrium disassociation constant (KD)..</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>
FC Image
Flow Cytometry - Anti-SESN1 antibody [EPR1930(2)]; Flow Cytometry analysis of permeabilized K562 cells labelling SESN1 with TA311066 at 1/100 dilution (red). Rabbit IgG (negative control) shown in green.</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>

 

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