Anti-SERPINE1 Antibody, EPR5373

Also for SERPINE1 (NM_000602)

Gene Name	Homo sapiens serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (SERPINE1), transcript variant 1
Synonyms:	PAI; PAI-1; PAI1; PLANH1
Immunogen	A synthetic peptide corresponding to residues in human PAI-1 was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR5373	Isotype
Species Reactivity	Human, Mouse	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB	Suggested Dilutions	WB: 1:1,000 - 10,000; IHC 1:250 - 500; ICC: 1:100 - 250; IP: 1:10 - 100;
Background	PAI-1 is a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the protein product are associated with thrombophilia (1).
Related Pathway	Adipogenesis Hemostasis Senescence and Autophagy TGF Beta Signaling Pathway

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WB Image

Western blot analysis on (A) fetal lung, (B) RAW 264.7, (C) HepG2, and (D) HT-1080 cell lysates using anti-PAI-1 RabMAb.

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Anti-SERPINE1 Antibody EPR5373

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