Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. Retinoid X receptor alpha is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators (1).
Related Pathway
Adipogenesis
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Western blot analysis on (A) MCF-7, (B) HeLa, (C) K562, (D) RAW 264.7, (E) PC-12, and (F) NIH/3T3 cell lysates using anti-Retinoid X receptor alpha RabMAb.
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