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Anti-REN Antibody EPR6433
|A synthetic peptide corresponding to residues in human Renin was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, FC
||WB: 1:1000 - 1:10000; FC: 1:10 - 1:100
|pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA|
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens renin (REN)|
Entrez Gene 5972 Human
|Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release, vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Mutations in Renin have been shown to cause familial hyperproreninemia (1). |
|Secreted ProteinDruggable Genome Renin-angiotensin system|
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Western blot - Anti-Prorenin antibody [EPR6433]; All lanes : Anti-Prorenin antibody [EPR6433] at 1/1000 dilution.Lane 1 : K562 lysate.Lane 2 : 293T lysate.Lane 3 : HepG2 lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 45 kDa.Observed band size : 47 kDa .
Other-Anti-Prorenin antibody [EPR6433](TA311049); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-Prorenin antibody [EPR6433]; Flow cytometric analysis of permeabilized K562 cells using TA311049 at 1/10 shown in red or a rabbit IgG negative control shown in green.