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Home Antibody All anti-PNP antibodies

Anti-PNP Antibody EPR5714

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SKU Description Amount Price Availability*  
TA311031
  • Rabbit Monoclonal antibody against Nucleoside Phosphorylase (PNP)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424829) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus in human Nucleoside Phosphorylase was used as an immunogen.
Clone NameEPR5714 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC/IF or IHC-P.

Reference Data

Target NameHomo sapiens purine nucleoside phosphorylase (PNP)
Alternative NameNP; PRO1837; PUNP
Database LinkNP_000261
Entrez Gene 4860 Human
FunctionNucleoside phosphorylase is an enzyme that reversibly catalyzes the phosphorolysis of purine nucleosides. It is trimeric, containing three identical subunits. Mutations that result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity, but they can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described.
Related PathwayStem cell - PluripotencyDruggable Genome Purine metabolismPyrimidine metabolismNicotinate and nicotinamide metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Nucleoside phosphorylase antibody [EPR5714]; All lanes : Anti-Nucleoside phosphorylase antibody [EPR5714] at 1/10000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : JAR cell lysate.Lane 3 : 293T cell lysate.Lane 4 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 32 kDa.
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