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Anti-PDGFRA Antibody EPR5480
Also for PDGFRA (NM_006206)
|A synthetic peptide corresponding to residues at the C-terminus of human PDGF Receptor alpha was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens platelet-derived growth factor receptor, alpha polypeptide (PDGFRA)|
|CD140A; PDGFR-2; PDGFR2; RHEPDGFRA|
Entrez Gene 5156 Human
Entrez Gene 18595 Mouse
Entrez Gene 25267 Rat
|PDGF Receptor alpha is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes (1). |
Cytokine-cytokine receptor interaction
MAPK signaling pathway
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Western blot - Anti-PDGF Receptor alpha antibody [EPR5480]; All lanes : Anti-PDGF Receptor alpha antibody [EPR5480] at 1/1000 dilution.Lane 1 : SH SY5Y cell lysate .Lane 2 : C2C12 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 122 kDa.Observed band size : 190 kDa .
Western blot - Anti-PDGF Receptor alpha antibody [EPR5480]; All lanes : Anti-PDGF Receptor alpha antibody [EPR5480] at 1/1000 dilution.Lane 1 : Human skeletal muscle lysate.Lane 2 : Human spleen lysate.Lane 3 : Human fetal brain lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 122 kDa.Observed band size : 190 kDa .