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Home Antibody All anti-PDGFRA antibodies

Anti-PDGFRA Antibody EPR5480

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311023
  • Rabbit Monoclonal antibody against PDGF Receptor alpha (PDGFRA)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416803) , 20ug
100ul 325 In Stock
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WB(2)
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Also for PDGFRA (NM_006206)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues at the C-terminus of human PDGF Receptor alpha was used as an immunogen.
Clone NameEPR5480 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens platelet-derived growth factor receptor, alpha polypeptide (PDGFRA)
Alternative NameCD140A; PDGFR-2; PDGFR2; RHEPDGFRA
Database LinkNP_006197
FunctionPDGF Receptor alpha is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes (1).
Related Pathway
Cytokine-cytokine receptor interaction
Focal Adhesion
MAPK signaling pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-PDGF Receptor alpha antibody [EPR5480]; All lanes : Anti-PDGF Receptor alpha antibody [EPR5480] at 1/1000 dilution.Lane 1 : SH SY5Y cell lysate .Lane 2 : C2C12 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 122 kDa.Observed band size : 190 kDa .
WB Image
Western blot - Anti-PDGF Receptor alpha antibody [EPR5480]; All lanes : Anti-PDGF Receptor alpha antibody [EPR5480] at 1/1000 dilution.Lane 1 : Human skeletal muscle lysate.Lane 2 : Human spleen lysate.Lane 3 : Human fetal brain lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 122 kDa.Observed band size : 190 kDa .

 

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