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Anti-PC Antibody EPR7366
|A synthetic peptide corresponding to residues in human Pyruvate Carboxylase was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens pyruvate carboxylase (PC), transcript variant 1|
|Pyruvate carboxylase requires biotin and ATP to catalyze the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron, which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this protein have been associated with pyruvate carboxylase deficiency (1). |
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Western blot - Anti-PCB antibody [EPR7366]; All lanes : Anti-PCB antibody [EPR7366] at 1/1000 dilution.Lane 1 : Human fetal kidney lysate.Lane 2 : HepG2 lysate.Lane 3 : Human fetal liver lysate.Lane 4 : A549 lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 130 kDa.
Western blot - Anti-PCB antibody [EPR7366]; All lanes : Anti-PCB antibody [EPR7366] at 1/1000 dilution.Lane 1 : Mouse brain lysate.Lane 2 : Rat brain lysate.Predicted band size : 130 kDa.
Other-Anti-PCB antibody [EPR7366](ab126707); Equilibrium disassociation constant (KD)..