Anti-PC Antibody, EPR7366

Also for PC (NM_000920)

Gene Name	Homo sapiens pyruvate carboxylase (PC), nuclear gene encoding mitochondrial protein, transcript variant 1
Synonyms:	PCB
Immunogen	A synthetic peptide corresponding to residues in human Pyruvate Carboxylase was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR7366	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB	Suggested Dilutions	WB: 1:1,000 - 10,000; IP: 1:10 - 100;
Background	Pyruvate carboxylase requires biotin and ATP to catalyze the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron, which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this protein have been associated with pyruvate carboxylase deficiency (1).
Related Pathway

* Shipping is in business days

* OriGene provides validated application data and protocol, with money back guarantee.

WB Image

Western blot analysis on (A) fetal kidney, (B) HepG2, (C) fetal liver, and (D) A549 lysates using anti-Pyruvate Carboxylase RabMAb.

WB Image

Western blot analysis on (A) mouse brain and (B) rat brain lysates using anti-Pyruvate Carboxylase RabMAb.

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

OriGene Antibodies in recent publications

Anti-PC Antibody EPR7366

TrueMAB™ Antibodies - Made against Authentic Protein Antigens