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Home Antibody All anti-NFKBIE antibodies

Anti-NFKBIE Antibody EPR901(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311004
  • Rabbit Monoclonal antibody against IkappaB epsilon (NFKBIE)
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for NFKBIE (NM_004556)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human IkappaB epsilon was used as an immunogen.
Clone NameEPR901(2) IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt.
Purification Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon (NFKBIE)
Alternative NameIKBE
Database LinkNP_004547
Entrez Gene 4794 Human
FunctionIkappaB epsilon, a novel member of the IkappaB family, has six consecutive ankyrin repeats. IkappaB epsilon interacts with different NF-kappaB proteins, including p65 (RelA), c-Rel, p50, and p52, in vitro and in vivo and inhibits the DNA-binding activity of both p50-p65 and p50-c-Rel complexes effectively. IkappaB epsilon displays differential induction in response to tumor necrosis factor alpha, interleukin-1, or phorbol ester stimulation compared to I kappaB alpha in non-B-cell lines. This protein provides an alternative mechanism for regulation of NF-kappaB-dependent transcription (1).
Related PathwayTranscription FactorsDruggable Genome T cell receptor signaling pathwayB cell receptor signaling pathwayNeurotrophin signaling pathwayAdipocytokine signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-IKB epsilon antibody [EPR901(2)]; All lanes : Anti-IKB epsilon antibody [EPR901(2)] at 1/1000 dilution.Lane 1 : THP-1 cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : A375 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 53 kDa.Observed band size : 45 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IKB epsilon antibody [EPR901(2)]; Immunohistochemical analysis of Paraffin-embedded Human tonsil tissue labelling IKB epsilon with TA311004 at 1/100 dilution.

 

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