Anti-NFKBIE Antibody, EPR901(2)

Also for NFKBIE (NM_004556)

Gene Name	Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon (NFKBIE)
Synonyms:	IKBE
Immunogen	A synthetic peptide corresponding to residues in human IkappaB epsilon was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR901(2)	Isotype
Species Reactivity	Human	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1:1,000 - 10,000; IHC 1:50 - 100; ICC: 1:25 - 50; FC: 1:10 - 100;
Background	IkappaB epsilon, a novel member of the IkappaB family, has six consecutive ankyrin repeats. IkappaB epsilon interacts with different NF-kappaB proteins, including p65 (RelA), c-Rel, p50, and p52, in vitro and in vivo and inhibits the DNA-binding activity of both p50-p65 and p50-c-Rel complexes effectively. IkappaB epsilon displays differential induction in response to tumor necrosis factor alpha, interleukin-1, or phorbol ester stimulation compared to I kappaB alpha in non-B-cell lines. This protein provides an alternative mechanism for regulation of NF-kappaB-dependent transcription (1).
Related Pathway	Apoptosis

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WB Image

Western blot analysis on (A) THP-1, (B) Jurkat, (C) HeLa, and (D) A375 cell lysates using anti-IkappaB epsilon RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IkappaB epsilon RabMAb.

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Anti-NFKBIE Antibody EPR901(2)

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