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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]

Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]

Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]

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Home All anti-NFKBIB antibodies

Anti-NFKBIB Antibody EPR5037

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA311003
  • Rabbit Monoclonal antibody against IKappaB-beta (NFKBIB)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424220) , 20ug
100ul $325 3-7 Days Add to Shopping Cart
WB(1)
IHC(1)
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Also for NFKBIB (NM_001001716)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody
Gene NameHomo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (NFKBIB), transcript variant 2
Synonyms:IKBB; TRIP9
ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human IKappaB-beta was used as an immunogen.
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone NameEPR5037 Isotype
Species ReactivityHuman Concentration
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:10,000 - 50,000; IHC 1:250 - 500;
BackgroundNFkB1 or NFkB2 is bound to REL, RELA, or RELB to form the NFkB complex. The NFkB complex is inhibited by IKappaB proteins, which inactivate NFkappaB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKappaB proteins by kinases (IKappaB-alpha or IKappaB-beta) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex (1).
Related Pathway
Apoptosis

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis on (A) Jurkat, (B) HeLa, (C) THP-1, and (D) MCF-7 cell lysates using anti-IKappaB-beta RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-IkappaB-beta RabMAB.

 

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