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Anti-ZNF217 Antibody EPR6362
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Also for ZNF217 (NM_006526)
|A synthetic peptide corresponding to residues on the C-terminus in human ZNF217 was used as an immunogen.|
||WB: 1:1,000 - 10,000; IP: 1:10 - 100; FC: 1:100 - 500;
|Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.|
|Homo sapiens zinc finger protein 217 (ZNF217)|
|ZNF217 is a Krüppel-like zinc finger protein that localizes to the nucleus and interacts with co-repressors and histone modifying proteins, suggesting that ZNF217 may be part of a transcriptional repressor complex. ZNF217 functions in apoptosis by attenuating apoptotic signals resulting from doxorubicin-induced DNA damage or from functionally compromised telomeres (1). It is implicated as a human oncoprotein based on its role in carcinogenesis (2). In particular, ZNF217 regulates ErbB3 expression in breast cancer (3).|
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Western blot analysis on (A) MCF-7, (B) PC-3, (C) Caco-2 cell lysates using anti-ZNF217 RabMAb.