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Home Antibody All anti-UCHL5 antibodies

Anti-UCHL5 Antibody EPR4896

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310918
  • Rabbit Monoclonal antibody against UCHL5 / UCH37
100ul 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human UCHL5 / UCH37 was used as an immunogen.
Clone NameEPR4896 IsotypeTissue culture supernatant
Species ReactivityHuman, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:500 - 1:1000; FC: 1:10 - 1:100
BufferDoes not react with Mouse. Is unsuitable for ICC.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC.

Reference Data

Target NameHomo sapiens ubiquitin carboxyl-terminal hydrolase L5 (UCHL5), transcript variant 1
Alternative NameCGI-70; INO80R; UCH-L5; UCH37
Database LinkNP_057068
FunctionUbiquitin carboxyl-terminal hydrolase isozyme L5 (UCHL5 / UCH37) is a protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains, and a deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. It is activated by ADRM1 and inhibited by interaction with NFRKB. UCHL5 / UCH37 associates with the proteasome 19S subunit in the cytoplasm, and the INO80 complex in the nucleus (1).
Related Pathway

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WB Image
Western blot - Anti-UCH37 antibody [EPR4896]; All lanes : Anti-UCH37 antibody [EPR4896] at 1/1000 dilution.Lane 1 : Human fetal kidney cell lysates.Lane 2 : 293T cell lysates.Lane 3 : NCCIT cell lysates.Lane 4 : SH-SY5Y cell lysates.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 38 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-UCH37 antibody [EPR4896]; TA310918, at 1/500 dilution, staining UCH37 in paraffin embedded Human kidney tissue by Immunohistochemistry.

 

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