Home Antibody All anti-UBE4B antibodies
Anti-UBE4B Antibody EPR7471
Also for UBE4B (NM_001105562)
|A synthetic peptide corresponding to residues in human UBE4B was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens ubiquitination factor E4B (UBE4B), transcript variant 1|
|E4; HDNB1; UBOX3; UFD2; UFD2A|
Entrez Gene 10277 Human
Entrez Gene 63958 Mouse
Entrez Gene 298652 Rat
|The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B is an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. It is also the strongest candidate in the neuroblastoma tumor suppressor (1). |
| Ubiquitin mediated proteolysis|
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Western blot - Anti-UBE4B antibody [EPR7471]; All lanes : Anti-UBE4B antibody [EPR7471] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : Raji cell lysate.Lane 3 : SK OV 3 cell lysate.Lane 4 : L929 cell lysate.Lane 5 : L6 cell lysate.Lane 6 : RAW264.7 cell lysate.Lane 7 : PC12 cell lysate.Lane 8 : NIH 3T3 cell lysate.Lane 9 : HeLa cell lysate.Lane 10 : K562 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP-conjugated goat anti-rabbit at 1/2000 dilution.Predicted band size : 146 kDa.