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Anti-UBE2C Antibody EPR5161(2)
Also for UBE2C (NM_007019)
|A synthetic peptide corresponding to residues in human UBE2C / UBCH10 was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA|
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens ubiquitin-conjugating enzyme E2C (UBE2C), transcript variant 1|
Entrez Gene 11065 Human
|The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C / UBCH10 is a member of the E2 ubiquitin-conjugating enzyme family. It is required for the destruction of mitotic cyclins and for cell cycle progression (1). |
|Druggable Genome Ubiquitin mediated proteolysis|
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Western blot - Anti-UBE2C antibody [EPR5161(2)]; All lanes : Anti-UBE2C antibody [EPR5161(2)] at 1/1000 dilution.Lane 1 : SW480 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : MCF7 cell lysate.Lane 4 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 20 kDa.
Other-Anti-UBE2C antibody [EPR5161(2)](TA310912); Equilibrium disassociation constant (KD)..