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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-UBE2C antibodies

Anti-UBE2C Antibody EPR5161(2)

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA310912
  • Rabbit Monoclonal antibody against UBE2C / UBCH10
  • FREE positive control: HEK293T cell transient overexpression lysate (LC416256) , 20ug
 100ul $325 3-7 Days Add to Shopping Cart
WB(1)
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Also for UBE2C (NM_007019)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens ubiquitin-conjugating enzyme E2C (UBE2C), transcript variant 1
Synonyms:dJ447F3.2; UBCH10
ImmunogenA synthetic peptide corresponding to residues in human UBE2C / UBCH10 was used as an immunogen.
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone NameEPR5161(2) Isotype
Species ReactivityHuman Concentration
Guaranteed Application *WB Suggested DilutionsWB: 1:10,000 - 50,000 (5 ng);
BackgroundThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C / UBCH10 is a member of the E2 ubiquitin-conjugating enzyme family. It is required for the destruction of mitotic cyclins and for cell cycle progression (1).
Related Pathway
Cell cycle

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis on (A) SW480, (B) HeLa, (C) MCF-7, and (D) 293T cell lysates using anti-UBE2C / UBCH10 RabMAb.

 

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