Anti-TRPM7 Antibody, EPR4582

Also for TRPM7 (NM_017672)

Gene Name	Homo sapiens transient receptor potential cation channel, subfamily M, member 7 (TRPM7)
Synonyms:	ALSPDC; CHAK; CHAK1; LTRPC7; TRP-PLIK
Immunogen	A synthetic peptide corresponding to residues near the C-terminus of human TRPM7 was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR4582	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, IF	Suggested Dilutions	WB: 1:1,000 - 10,000; IP: 1:10 - 100;
Background	TRPM7 is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. Defects in TRPM7 are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam (1).
Related Pathway

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WB Image

Western blot analysis on (A) HeLa, (B) HuT-78, (C) JAR, and (D) HepG2 cell lysates using anti-TRPM7 RabMAb.

IF Image

Immunofluorescent staining of HeLa cells using anti-TRPM7 RabMAb.

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Anti-TRPM7 Antibody EPR4582

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