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Home Antibody All anti-TMEFF2 antibodies

Anti-TMEFF2 Antibody EPR6386

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310900
  • Rabbit Monoclonal antibody against TMEFF2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402517) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
Assay(1)
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Also for TMEFF2 (NM_016192)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in the intracellular domain in human TMEFF2 was used as an immunogen.
Clone NameEPR6386 IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsIHC-P: 1:50 - 1:100; ICC/IF: 1:50 - 1:100; FC: 1:10 - 1:100; WB: 1:1000 - 1:10000
BufferDoes not react with Mouse, Rat. Is unsuitable for IP.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2)
Alternative NameCT120.2; HPP1; TENB2; TPEF; TR
Database LinkNP_057276
FunctionTMEFF2 is a survival factor for hippocampal and mesencephalic neurons (1). Soluble forms of TMEFF2’s extracellular domain have been reported to weakly stimulate erbB-4/HER4 tyrosine phosphorylation in gastric cancer cells, and they promote the survival of mesencephalic dopaminergic neurons. Elevated TMEFF2 expression is associated with higher prostate cancer grade and hormone independence (2). TMEFF2 is widely expressed in the brain, including hippocampal cornu ammonis, dentate gyrus, and substantia nigra pars compacta (1).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-TMEFF2 antibody [EPR6386]; All lanes : Anti-TMEFF2 antibody [EPR6386] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : LnCaP cell lysate.Lane 3 : Caco 2 cell lysate.Lane 4 : SW480 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.developed using the ECL technique.Predicted band size : 41 kDa.
Assay Image
Other-Anti-TMEFF2 antibody [EPR6386](TA310900); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEFF2 antibody [EPR6386]; Immunohistochemical analysis of formailin-fixed, paraffin-embedded Human prostatic hyperplasia tissue staining TMEFF2 using TA310900 at a 1/50 dilution.

 

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