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Home Antibody All anti-SSRP1 antibodies

Anti-SSRP1 Antibody EPR7894

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310878
  • Rabbit Monoclonal antibody against SSRP1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418869) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
FC(1)
Assay(1)
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Also for SSRP1 (NM_003146)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SSRP1 was used as an immunogen.
Clone NameEPR7894 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:10000 - 1:50000; FC: 1:100 - 1:500
Predicted MW Explanation 81 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens structure specific recognition protein 1 (SSRP1)
Alternative NameFACT; FACT80; T160
Database LinkNP_003137
Entrez Gene 6749 Human
Entrez Gene 20833 Mouse
Entrez Gene 81785 Rat
FunctionSSRP1 is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. SSRP1 contains a high mobility group box that most likely constitutes the structure recognition element for cisplatin-modified DNA. It also functions as a co-activator of the transcriptional activator p63 (1).
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-SSRP1 antibody [EPR7894]; All lanes : Anti-SSRP1 antibody [EPR7894] at 1/10000 dilution.Lane 1 : K562 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : MOLT4 cell lysate.Lane 4 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 81 kDa.
Assay Image
Other-Anti-SSRP1 antibody [EPR7894](TA310878); Equilibrium disassociation constant (KD)..
FC Image
Flow Cytometry - Anti-SSRP1 antibody [EPR7894]; TA310878, at 1/100 dilution, staining SSRP1 in permeabilized MOLT4 cells by Flow cytometry (red) or Rabbit IgG negative control (green).

 

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