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Home Antibody All anti-SP1 antibodies

Anti-SP1 Antibody EPR6662(B)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310869
  • Rabbit Monoclonal antibody against SP1
100ul 325 3-7 Days
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WB(1)
IHC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SP1 was used as an immunogen.
Clone NameEPR6662(B) IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens Sp1 transcription factor (SP1), transcript variant 1
Alternative Namespecificity protein 1; Sp1 transcription factor
Database LinkNP_612482
FunctionTranscription factor SP1 is a member of the Sp/XKLF (Specificity protein/Krüppel-like factor) family. It regulates transcription by dynamically recruiting and forming complexes with many factors associated with transcription. Although SP1 has been described as a transcriptional activator, it can also act as a repressor (1). SP1 has been implicated in the expression of numerous genes involved in many aspects of cellular life such as metabolism, cell growth, differentiation, angiogenesis and apoptosis regulation (1). Although it is a ubiquitous protein that targets both core promoters and enhancers, SP1 is also highly expressed in various cancers of the stomach, colon and rectum, pancreas, breast, and thyroid (2).
Related Pathway
Adipogenesis
EGFR1 Signaling Pathway
TGF Beta Signaling Pathway

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WB Image
Western blot - Anti-SP1 antibody [EPR6662(B)]; All lanes : Anti-SP1 antibody [EPR6662(B)] at 1/1000 dilution.Lane 1 : Ramos cell lysates.Lane 2 : HeLa cell lysates.Lane 3 : K562 cell lysates.Lane 4 : Raji cell lysates.Lysates/proteins at 10 µg per lane.Predicted band size : 81 kDa.
Assay Image
Other-Anti-SP1 antibody [EPR6662(B)](TA310869); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SP1 antibody [EPR6662(B)]; TA310869, at 1/100 dilution staining SP1 in paraffin-embedded Human colon tissue, by Immunohistochemistry.

 

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