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Anti-SCAI Antibody EPR4128
Also for SCAI (NM_001144877)
|A synthetic peptide corresponding to residues in human SCAI was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, Assay, FC
||WB: 1:1000 - 1:10000; FC: 1:100 - 1:500
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens suppressor of cancer cell invasion (SCAI), transcript variant 2|
Entrez Gene 286205 Human
Entrez Gene 320271 Mouse
Entrez Gene 690538 Rat
|SCAI, also known as Suppressor of Cancer Cell Invasion, is a tumor suppressor that functions to suppress MKL1-induced SRF transcriptional activity (1). It is a regulator of cell migration and appears to be involved in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway (2). SCAI localizes in the nucleus, where it binds and inhibits the myocardin-related transcription factor MAL by forming a ternary complex with serum response factor (SRF) (3).|
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Western blot - Anti-SCAI antibody [EPR4128]; All lanes : Anti-SCAI antibody [EPR4128] at 1/1000 dilution.Lane 1 : Human Thymus lysate.Lane 2 : Human Thyroid lysate.Lane 3 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat-anti-rabbit HRP at 1/2000 dilution.Predicted band size : 70 kDa.
Other-Anti-SCAI antibody [EPR4128](TA310840); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-SCAI antibody [EPR4128]; TA310840 at 1/100 dilution staining SCAI in SH-SY5Y cells by Flow cytometry (red) compared to a nonspecific negative control antibody (Green).