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Home Antibody All anti-SCAI antibodies

Anti-SCAI Antibody EPR4128

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310840 Rabbit Monoclonal antibody against SCAI 100ul $325 In Stock
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WB(1)
FC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SCAI was used as an immunogen.
Clone NameEPR4128 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, Assay, FC Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:100 - 1:500
Predicted MW Explanation 70 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens suppressor of cancer cell invasion (SCAI), transcript variant 2
Alternative NameC9orf126; NET40
Database LinkNP_001138349
Entrez Gene 286205 Human
Entrez Gene 320271 Mouse
Entrez Gene 690538 Rat
FunctionSCAI, also known as Suppressor of Cancer Cell Invasion, is a tumor suppressor that functions to suppress MKL1-induced SRF transcriptional activity (1). It is a regulator of cell migration and appears to be involved in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway (2). SCAI localizes in the nucleus, where it binds and inhibits the myocardin-related transcription factor MAL by forming a ternary complex with serum response factor (SRF) (3).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-SCAI antibody [EPR4128]; All lanes : Anti-SCAI antibody [EPR4128] at 1/1000 dilution.Lane 1 : Human Thymus lysate.Lane 2 : Human Thyroid lysate.Lane 3 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat-anti-rabbit HRP at 1/2000 dilution.Predicted band size : 70 kDa.
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Other-Anti-SCAI antibody [EPR4128](TA310840); Equilibrium disassociation constant (KD)..
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Flow Cytometry - Anti-SCAI antibody [EPR4128]; TA310840 at 1/100 dilution staining SCAI in SH-SY5Y cells by Flow cytometry (red) compared to a nonspecific negative control antibody (Green).
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