Anti-RYK Antibody, EPR5169(2)

Also for RYK (NM_001005861)

Gene Name	Homo sapiens receptor-like tyrosine kinase (RYK), transcript variant 1
Synonyms:	D3S3195; JTK5; JTK5A; RYK1
Immunogen	A synthetic peptide corresponding to residues in human RYK was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR5169(2)	Isotype
Species Reactivity	Human	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1:1,000 - 10,000; IHC 1:50 - 100; ICC: 1:50 - 100; FC: 1:10 - 100;
Background	RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. It belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism (1).
Related Pathway

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WB Image

Western blot analysis on (A) 293T, (B) MCF-7, and (C) Jurkat cell lysates using anti-RYK RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-RYK RabMAb.

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Anti-RYK Antibody EPR5169(2)

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