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Anti-RPE Antibody EPR7464

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310827
  • Rabbit Monoclonal antibody against RPE
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416326) , 20ug
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human RPE was used as an immunogen.
Clone NameEPR7464 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000; IP: 1:10 - 1:100
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens ribulose-5-phosphate-3-epimerase (RPE), transcript variant 2
Alternative NameRPE2-1
Database LinkNP_008847
FunctionRPE is an iron enzyme with a mononuclear metal atom that binds the carbonyl and carboxylate moieties of ribulose-5-phosphate, facilitating epimerization by stabilizing the deprotonated anionic intermediate. It employs a ferrous iron atom as a solvent-exposed cofactor, and hydrogen peroxide (H2O2) rapidly oxidizes this metal in a Fenton reaction. Thus, RPE is rapidly damaged by H2O2, similar to Fe–S dehydratases (1).
Related Pathway

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WB Image
Western blot - Anti-RPE antibody [EPR7464]; All lanes : Anti-RPE antibody [EPR7464] at 1/1000 dilution.Lane 1 : K562 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : 293T cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP-conjugated goat anti-rabbit at 1/2000 dilution.Predicted band size : 25 kDa.

 

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