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Anti-PTX3 Antibody EPR6699


Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against PTX3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419080) , 20ug Explanation
100ul 325 3-7 Days
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Also for PTX3 (NM_002852)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PTX3 was used as an immunogen.
Clone NameEPR6699 IsotypeTissue culture supernatant
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; FC: 1:10 - 1:100
BufferDoes not react with Rat. Is unsuitable for ICC or IHC-P.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC or IHC-P.

Reference Data

Target NameHomo sapiens pentraxin 3, long (PTX3)
Alternative NameTNFAIP5; TSG-14
Database LinkNP_002843
Entrez Gene 5806 Human
Entrez Gene 19288 Mouse
FunctionThe long pentraxin 3 PTX3 is a member of a complex superfamily of multifunctional proteins, produced by innate-immunity cells in response to proinflammatory signals and Toll-like receptor engagement (1). PTX3 is a prototypic soluble pattern recognition molecule (PRM), thus the recognition of a microbial component by PTX3 can amplify the inflammatory response. It plays a role in the regulation of complement-mediated immune responses (2). PTX3 seems to also have unique immunoregulatory functions such as modulating the phagocytic uptake of apoptotic cells by macrophages and dendritic cells (3). A mutation in PTX3 is associated with a severe defect in female fertility (1).
Related PathwaySecreted Protein

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Pentraxin 3 antibody [EPR6699]; All lanes : Anti-Pentraxin 3 antibody [EPR6699] at 1/1000 dilution.Lane 1 : HL-60 treated with Dexamethasone lysate.Lane 2 : HL-60 lysate.Lane 3 : Human spleen lysate.Lane 4 : NIH/3T3 cell lysate.Lane 5 : HUVEC lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 42 kDa.Observed band size : 42 kDa.
Assay Image
Other-Anti-Pentraxin 3 antibody [EPR6699](TA310796); Equilibrium disassociation constant (KD)..
FC Image
Flow Cytometry - Anti-Pentraxin 3 antibody [EPR6699]; Flow cytometric analysis of permeabilized HUVEC cells using TA310796 at 1/10 dilution (red) or a rabbit IgG (negative) (green).


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