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Anti-PPP6C Antibody EPR8764
Also for PPP6C (NM_001123355)
|A synthetic peptide corresponding to residues on the C-terminus in human PPP6C was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IF
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IHC-P.
|Homo sapiens protein phosphatase 6, catalytic subunit (PPP6C), transcript variant 1|
Entrez Gene 5537 Human
Entrez Gene 67857 Mouse
Entrez Gene 171121 Rat
|PPP6C is the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. The N-terminal domain of PPP6C restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. PPP6C also downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7 (1).|
|PhosphataseDruggable Genome |
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Western blot - Anti-PPP6C antibody [EPR8764]; All lanes : Anti-PPP6C antibody [EPR8764] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Fetal thymus lysate.Lane 3 : 293T cell lysate.Lane 4 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 35 kDa.
Other-Anti-PPP6C antibody [EPR8764](TA310774); Equilibrium disassociation constant (KD)..
Immunocytochemistry/ Immunofluorescence - Anti-PPP6C antibody [EPR8764]; Immunofluorescent analysis of HeLa cells labelling PPP6C with TA310774 at 1/100 dilution.