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Anti-PMS1 Antibody EPR8058
Also for PMS1 (NM_000534)
|A synthetic peptide corresponding to residues in human PMS1 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
|WB, ASSAY, FC
||WB: 1:10000 - 1:50000; FC: 1:10 - 1:100
|Does not react with Mouse, Rat. Is unsuitable for ICC,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens PMS1 postmeiotic segregation increased 1 (S. cerevisiae) (PMS1), transcript variant 1|
|HNPCC3; hPMS1; PMSL1|
|PMS1 belongs to the DNA mismatch repair mutL/hexB family. It is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other proteins involved in the HNPCC phenotype, which is also known as Lynch syndrome (1). |
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Western blot - Anti-PMS1 antibody [EPR8058]; All lanes : Anti-PMS1 antibody [EPR8058] at 1/10000 dilution.Lane 1 : HeLa cell lysates.Lane 2 : Jurkat cell lysates.Lane 3 : Molt-4 cell lysates.Lane 4 : HepG2 cell lysates .Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit.Predicted band size : 106 kDa.Observed band size : 105 kDa .
Other-Anti-PMS1 antibody [EPR8058](ab129020); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-PMS1 antibody [EPR8058]; Flow cytometric analysis of permeabilized Jurkat cells using ab129020 at 1/10 (red) or a rabbit IgG negative (green).