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Anti-PMS1 Antibody EPR8058


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against PMS1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424657) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PMS1 was used as an immunogen.
Clone NameEPR8058 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:10000 - 1:50000; FC: 1:10 - 1:100
BufferpH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens PMS1 postmeiotic segregation increased 1 (S. cerevisiae) (PMS1), transcript variant 1
Alternative NameHNPCC3; hPMS1; PMSL1
Database LinkNP_000525
Entrez Gene 5378 Human
FunctionPMS1 belongs to the DNA mismatch repair mutL/hexB family. It is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other proteins involved in the HNPCC phenotype, which is also known as Lynch syndrome (1).
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-PMS1 antibody [EPR8058]; All lanes : Anti-PMS1 antibody [EPR8058] at 1/10000 dilution.Lane 1 : HeLa cell lysates.Lane 2 : Jurkat cell lysates.Lane 3 : Molt-4 cell lysates.Lane 4 : HepG2 cell lysates .Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit.Predicted band size : 106 kDa.Observed band size : 105 kDa .
Other-Anti-PMS1 antibody [EPR8058](TA310769); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-PMS1 antibody [EPR8058]; Flow cytometric analysis of permeabilized Jurkat cells using TA310769 at 1/10 (red) or a rabbit IgG negative (green).


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