OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-PLAU antibodies

Anti-PLAU Antibody EPR6273

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310763
  • Rabbit Monoclonal antibody against PLAU
100ul 325 In Stock
Add to Shopping Cart
WB(1)
FC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PLAU was used as an immunogen.
Clone NameEPR6273 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsFC: 1:100 - 1:500; IP: 1:10 - 1:100; WB: 1:1000 - 1:10000
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC/IF or IHC-P.

Reference Data

Target NameHomo sapiens plasminogen activator, urokinase (PLAU), transcript variant 2
Alternative NameATF; BDPLT5; QPD; u-PA; UPA; URK
Database LinkNP_001138503
FunctionPLAU is a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific mutation in PLAU may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. It converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor (1).
Related Pathway
Hemostasis
Wnt Signaling Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Urokinase antibody [EPR6273]; All lanes : Anti-Urokinase antibody [EPR6273] at 1/1000 dilution.Lane 1 : PC3 cell lysate.Lane 2 : LNCaP cell lysate.Lane 3 : MCF7 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.developed using the ECL technique.Predicted band size : 49 kDa.</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>
Assay Image
Other-Anti-Urokinase antibody [EPR6273](TA310763); Equilibrium disassociation constant (KD)..</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>
FC Image
Flow Cytometry - Anti-Urokinase antibody [EPR6273]; Flow cytometry analysis of permeabilized MCF7 cells staining Urokinase using TA310763 at a 1/100 dilution (red) or a rabbit IgG negative control (green).</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title