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Anti-PLAGL1 Antibody EPR7523
Also for PLAGL1 (NM_001080951)
|A synthetic peptide corresponding to residues on the C-terminus in human PLAGL1 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
|WB, ASSAY, FC
||WB: 1:10000 - 1:50000; FC: 1:10 - 1:100
|Does not react with Mouse, Rat. Is unsuitable for ICC,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens pleiomorphic adenoma gene-like 1 (PLAGL1), transcript variant 3|
|LOT1; ZAC; ZAC1|
|PLAGL1 is a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, its overexpression during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). PLAGL1 is imprinted, with preferential expression of the paternal allele in many tissues; however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters (1).|
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Western blot - Anti-PLAGL1 / ZAC antibody [EPR7523]; All lanes : Anti-PLAGL1 / ZAC antibody [EPR7523] at 1/10000 dilution.Lane 1 : Human fetal liver lysate.Lane 2 : Human fetal kidney lysate.Lane 3 : 293T cell lysate.Lane 4 : HepG2 cell lysate.Lane 5 : SH-SY5Y cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 51 kDa.Observed band size : 51 kDa.
Other-Anti-PLAGL1 / ZAC antibody [EPR7523](ab129063); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-PLAGL1 / ZAC antibody [EPR7523]; ab129063 at 1/10 dilution staining PLAGL1 / ZAC in permeabilized HepG2 cells by Flow Cytometry (red) or a rabbit IgG negative (green).