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Anti-PIAS2 Antibody EPR2582(2)
Also for PIAS2 (NM_004671)
|A synthetic peptide corresponding to residues in human PIAS2 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; ICC/IF: 1:250 - 1:500
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,IHC-P or IP.
|Homo sapiens protein inhibitor of activated STAT, 2 (PIAS2), transcript variant beta|
|ARIP3; DIP; MIZ; MIZ1; PIASX; PIASX-ALPHA; PIASX-BETA; SIZ2; ZMIZ4|
|PIAS2 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. It plays a crucial role as a transcriptional coregulator in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway (1). |
Jak-STAT signaling pathway
TGF Beta Signaling Pathway
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Western blot - Anti-PIAS2 antibody [EPR2582(2)]; All lanes : Anti-PIAS2 antibody [EPR2582(2)] at 1/1000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : Human fetal kidney tissue lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 68 kDa.