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Home Antibody All anti-PCK1 antibodies

Anti-PCK1 Antibody EPR6938

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310742
  • Rabbit Monoclonal antibody against PCK1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419231) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
Assay(1)
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Also for PCK1 (NM_002591)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PCK1 was used as an immunogen.
Clone NameEPR6938 IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:10000 - 1:50000; IHC-P: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IP.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens phosphoenolpyruvate carboxykinase 1 (soluble) (PCK1)
Alternative NamePEPCK-C; PEPCK1; PEPCKC
Database LinkNP_002582
FunctionPCK1 is a main control point for the regulation of gluconeogenesis. It is a cytosolic enzyme, along with GTP, that catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of PCK1 can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in PCK1 are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of this protein also has been characterized (1).
Related Pathway
Adipogenesis

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-PCK1 antibody [EPR6938]; All lanes : Anti-PCK1 antibody [EPR6938] at 1/10000 dilution.Lane 1 : Human fetal kidney tissue lysate.Lane 2 : Human adipose tissue lysate.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 69 kDa.Observed band size : 69 kDa.
Assay Image
Other-Anti-PCK1 antibody [EPR6938](TA310742); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PCK1 antibody [EPR6938]; Immunohistochemical analysis of paraffin-embedded Human liver tissue labelling PCK1 with TA310742 at 1/100.

 

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