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Anti-NR5A2 Antibody EPR7000
Also for NR5A2 (NM_003822)
|A synthetic peptide corresponding to residues in human NR5A2 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens nuclear receptor subfamily 5, group A, member 2 (NR5A2), transcript variant 2|
|B1F; B1F2; CPF; FTF; FTZ-F1; FTZ-F1beta; hB1F-2; LRH-1; LRH1|
Entrez Gene 2494 Human
Entrez Gene 26424 Mouse
Entrez Gene 60349 Rat
|NR5A2 is a nuclear receptor originally identified in the liver and mostly known for its regulatory role in cholesterol and bile acid homeostasis. It is a key regulator of intestinal function, coordinating unanticipated actions, such as cell renewal and local immune function with important implications to common intestinal diseases, including colorectal cancer and inflammatory bowel disease. Unlike most of the other nuclear receptors, liver NR5A2 acts as a constitutively active transcription factor (1). Furthermore, NR5A2 functions in steroidogenesis in the gonad and intestine (2).|
|Nuclear Hormone ReceptorTranscription FactorsDruggable Genome Maturity onset diabetes of the young|
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Western blot - Anti-NR5A2 / LRH1 antibody [EPR7000]; All lanes : Anti-NR5A2 / LRH1 antibody [EPR7000] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : BxPC3 cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : MCF7 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti rabbit at 1/2000 dilution.Predicted band size : 61 kDa.Observed band size : 65 kDa .