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Home Antibody All anti-NEK6 antibodies

Anti-NEK6 Antibody EPR5283

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310720
  • Rabbit Monoclonal antibody against NEK6
  • FREE positive control: HEK293T cell transient overexpression lysate (LC428635) , 20ug
100ul $325 3-7 Days
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WB(1)
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Also for NEK6 (NM_001145001)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human NEK6 was used as an immunogen.
Clone NameEPR5283 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens NIMA-related kinase 6 (NEK6), transcript variant 1
Alternative NameSID6-1512
Database LinkNP_001138473
FunctionNEK6 is a member of the mammalian NIMA-related kinases (1). It is involved in the control of mitotic spindle formation. NEK6 kinase activity is up-regulated in M phase. Expression of an inactive NEK6 mutant arrested cells in M phase and interfered with chromosome segregation. It is suggested that NEK6 is required for cell cycle progression through mitosis and demonstrate that loss of NEK6 function leads to defective mitosis and apoptosis (2).
Related Pathway

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WB Image
Western blot - Anti-NEK6 antibody [EPR5283]; All lanes : Anti-NEK6 antibody [EPR5283] at 1/1000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : 293T cell lysate.Lane 4 : HT1080 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 36 kDa.

 

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