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Home Antibody All anti-MUC2 antibodies

Anti-MUC2 Antibody EPR6145

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310701
  • Rabbit Monoclonal antibody against MUC2
100ul 325 3-7 Days
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IHC(6)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human MUC2 was used as an immunogen.
Clone NameEPR6145 IsotypeIgG
Species ReactivityRat, Human (Does not react with: Mouse) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *ASSAY, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; FC: 1:10 - 1:100; ICC/IF: 1:50 - 1:100
Predicted MW Explanation 540 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Does not react with Mouse

Reference Data

Target NameHomo sapiens mucin 2, oligomeric mucus/gel-forming (MUC2)
Alternative NameMLP; MUC-2; SMUC
Database LinkNP_002448
Entrez Gene 4583 Human
Entrez Gene 24572 Rat
FunctionMUC2 is a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. MUC2 is secreted and forms an insoluble mucous barrier that protects the gut lumen. It polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight (1). It undergoes proteolytic cleavage in the outer mucus layer of the colon, contributing to the expanded volume and loose nature of this layer which allows for bacterial colonization in contrast to the inner mucus layer which is dense and devoid of bacteria (2).
Related Pathway Vibrio cholerae infection

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Assay Image
Other-Anti-MUC2 antibody [EPR6145](TA310701); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC2 antibody [EPR6145]; Immunohistochemical analysis of paraffin embedded Human colon tissue labelling MUC2 with TA310701 at 1/250.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-MUC2 antibody [EPR6145](TA310701); Immunohistochemical analysis of paraffin embedded Human Skeletal muscle tissue using TA310701 showing -ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-MUC2 antibody [EPR6145](TA310701); Immunohistochemical analysis of paraffin embedded normal Human brain tissue using TA310701 showing -ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-MUC2 antibody [EPR6145](TA310701); Immunohistochemical analysis of paraffin embedded normal Human tonsil tissue using TA310701 showing -ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-MUC2 antibody [EPR6145](TA310701); Immunohistochemical analysis of paraffin embedded Human Breast carcinoma tissue using TA310701 showing -ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-MUC2 antibody [EPR6145](TA310701); Immunohistochemical analysis of paraffin embedded Human Colonic adenocarcinoma tissue using TA310701 showing +ve staining.

 

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