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Anti-MC5R Antibody EPR8386
Also for MC5R (NM_005913)
|A synthetic peptide corresponding to residues in the extracellular domain of human MC5R was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; FC: 1:10 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for ICC or IP.
|Homo sapiens melanocortin 5 receptor (MC5R)|
|MC5R is a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. It is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation (1). MC5R is expressed in the brain but not in the melanoma cells (2).|
Signaling by GPCR
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Western blot - Anti-MC5 Receptor antibody; All lanes : Anti-MC5 Receptor antibody [EPR8386] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : K562 cell lysate.Lane 3 : U-87 MG cell lysate.Lane 4 : HepG2 cell lysate.Lane 5 : Human fetal brain lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 37 kDa.
Other-Anti-MC5 Receptor antibody [EPR8386](ab133656); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MC5 Receptor antibody; Immunohistochemical analysis of paraffin-embedded Human brain tissue labelling MC5 Receptor with ab133656 at 1/50 dilution.